Sunday, January 18, 2026

Helicobacter pylori Genotyping from American Indigenous Groups Shows Novel Amerindian vacA and cagA Alleles and Asian, African and European Admixture

Authors: Margarita Camorlinga-Ponce, Guillermo Perez-Perez, Gerardo Gonzalez-Valencia, Irma Mendoza, Rosenda Peñaloza-Espinosa, Irma Ramos, Dangeruta Kersulyte, Adriana Reyes-Leon, Carolina Romo, Julio Granados, Leopoldo Muñoz, Douglas E. Berg, Javier Torres

DOI: 10.1371/journal.pone.0027212

Abstract Summary

Mexican indigenous communities harbor unique Helicobacter pylori strains showing novel Amerindian genetic variants. Researchers studying Tarahumara, Huichol, and Nahua groups found that while most H. pylori isolates were Western type, some formed distinct Amerindian clusters in virulence genes cagA and vacA, shared with other indigenous American populations. These strains represent admixtures of Asian, European, and African lineages.

Why Brain? 🧠

Indigenous Mexican populations harbor unique H. pylori strains with novel Amerindian genetic variants, showing Asian, European, and African admixture, revealing bacterial evolution alongside human migration.

License: CC BY.


The image is AI-generated for illustrative purposes only. Courtesy of Midjourney.

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