Authors: Marion Mortamais, Christelle Reynes, Adam M. Brickman, Frank A. Provenzano, Jordan Muraskin, Florence Portet, Claudine Berr, Jacques Touchon, Alain Bonafé, Emmanuelle le Bars, Jerome J. Maller, Chantal Meslin, Robert Sabatier, Karen Ritchie, Sylvaine Artero
DOI: 10.1371/journal.pone.0056972
Abstract Summary
White matter brain lesions increase dementia risk, but location matters. A 7-year study of 426 healthy seniors found that high total lesion volume combined with clustering in the temporal brain region significantly predicted cognitive decline. This pattern emerged before symptoms appeared, offering a potential early warning system for identifying at-risk individuals.
Why Brain? 🧠
Temporal lobe white matter lesions combined with high total lesion load predict dementia risk up to 7 years before symptoms, enabling earlier identification of at-risk patients.
License: CC BY.
The image is AI-generated for illustrative purposes only. Courtesy of Midjourney.
