Authors: Martin Voss, Manfred Nimtz, Silke Leimkühler
DOI: 10.1371/journal.pone.0028170
Abstract Summary
Researchers reveal how Mycobacteria use two distinct proteins—MoeZR and MoeBR—in molybdenum cofactor (Moco) biosynthesis. While both proteins sulfurate MoaD proteins for Moco production, only MoeZR plays a dual role, also participating in cysteine biosynthesis. MoeBR, acquired through horizontal gene transfer, functions exclusively in non-essential Moco pathways.
Why Brain? 🧠
Mycobacterial MoeZR protein uniquely functions in both molybdenum cofactor and cysteine biosynthesis pathways, while related protein MoeBR only affects molybdenum metabolism, revealing dual metabolic roles.
License: CC BY.
The image is AI-generated for illustrative purposes only. Courtesy of Midjourney.
