Thursday, March 5, 2026

Making Co-Enrolment Feasible for Randomised Controlled Trials in Paediatric Intensive Care

Authors: Katie Harron, Twin Lee, Tracy Ball, Quen Mok, Carrol Gamble, Duncan Macrae, Ruth Gilbert

DOI: 10.1371/journal.pone.0041791

Abstract Summary

Co-enrolling critically ill children in multiple trials simultaneously appears feasible without compromising recruitment. In a study of two pediatric intensive care trials, units that allowed co-enrollment maintained similar consent rates to single-trial approaches. Despite concerns about overwhelming parents, 49% of families consented to both studies when offered. These findings suggest co-enrollment could accelerate research delivery in PICUs.

Why Brain? ๐Ÿง 

Study shows enrolling critically ill children in multiple trials simultaneously is feasible without reducing participation rates, potentially accelerating pediatric intensive care research.

License: CC BY.


The image is AI-generated for illustrative purposes only. Courtesy of Midjourney.

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