Sunday, January 18, 2026

Treatment Response of Cystic Echinococcosis to Benzimidazoles: A Systematic Review

Authors: Marija Stojkovic, Marcel Zwahlen, Antonella Teggi, Kamenna Vutova, Carmen M. Cretu, Roberto Virdone, Polyxeni Nicolaidou, Nazan Cobanoglu, Thomas Junghanss

DOI: 10.1371/journal.pntd.0000524

Abstract Summary

Benzimidazole drugs for cystic echinococcosis show limited effectiveness, with only 40-75% of cysts responding after 1-2 years depending on type and size. Critically, 25% of initially responsive cysts reactivate within 2 years, and relapse rates reach 60% after repeat treatments. This large study of 711 patients reveals benzimidazole efficacy has been overstated, highlighting the urgent need for controlled trials.

Why Brain? 🧠

Benzimidazole drugs for parasitic liver cysts show limited long-term success, with 40% of cysts remaining or becoming active after 2 years and frequent relapses, indicating need for better treatments.

License: CC BY.


The image is AI-generated for illustrative purposes only. Courtesy of Midjourney.

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