Saturday, December 6, 2025

Feasibility of Modified Surviving Sepsis Campaign Guidelines in a Resource-Restricted Setting Based on a Cohort Study of Severe S. Aureus Sepsis

Authors: Weera Mahavanakul, Emma K. Nickerson, Pramot Srisomang, Prapit Teparrukkul, Pichet Lorvinitnun, Mingkwan Wongyingsinn, Wirongrong Chierakul, Maliwan Hongsuwan, T. Eoin West, Nicholas P. Day, Direk Limmathurotsakul, Sharon J. Peacock

DOI: 10.1371/journal.pone.0029858

Abstract Summary

Study in Thailand shows modified sepsis care guidelines can work in resource-limited hospitals. Researchers found that while many recommended interventions were available, their use was inconsistent. By creating two practical care bundles—one for general wards, one for ICUs—focusing on basics like monitoring, antibiotics, and fluids, they identified feasible improvements that could reduce the 53% mortality rate.

Why Brain? 🧠

Modified sepsis guidelines adapted to resource-limited settings in Thailand showed feasible implementation of core interventions on general wards, potentially improving survival in severe sepsis without requiring costly resources.


The image is AI-generated for illustrative purposes only. Courtesy of Midjourney.

share this recipe:
Facebook
X
Email
Print

Still hungry? Here’s more