Authors: Vanesa Bol, Fanny Desjardins, Brigitte Reusens, Jen-Luc Balligand, Claude Remacle
DOI: 10.1371/journal.pone.0012656
Abstract Summary
Early nutritional mismatch from catch-up growth after fetal protein restriction leads to hypertension in adult mice, independent of obesity. Offspring exposed to low-protein diets in utero showed elevated blood pressure, altered heart rate, and disrupted circadian rhythms at 9 months, with higher stress hormones. However, atherosclerosis development was linked to obesogenic diet, not early nutrition.
Why Brain? 🧠
Early nutritional mismatch from fetal protein restriction followed by catch-up growth programs hypertension in adult mice independent of obesity, but doesn’t accelerate atherosclerosis development.
The image is AI-generated for illustrative purposes only. Courtesy of Midjourney.
