Sunday, November 30, 2025

Genome Sequence of a Lancefield Group C Streptococcus zooepidemicus Strain Causing Epidemic Nephritis: New Information about an Old Disease

Authors: Stephen B. Beres, Ricardo Sesso, Sergio Wyton L. Pinto, Nancy P. Hoe, Stephen F. Porcella, Frank R. DeLeo, James M. Musser

DOI: 10.1371/journal.pone.0003026

Abstract Summary

Researchers sequenced the genome of a Streptococcus strain that caused a severe kidney disease outbreak in Brazil, revealing new insights into post-streptococcal glomerulonephritis. The analysis challenges long-held beliefs about disease mechanisms and identifies unique features including collagen-like proteins with integrin-binding motifs, offering fresh leads for understanding this preventable kidney condition.

Why Brain? đź§ 

Genome sequencing of a streptococcal strain from a severe Brazilian nephritis outbreak reveals unexpected findings that challenge long-held beliefs about kidney disease mechanisms, opening new research directions.


The image is AI-generated for illustrative purposes only. Courtesy of Midjourney.

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