Authors: Frank Ludewig, Anke Hüser, Hillel Fromm, Linda Beauclair, Nicolas Bouché
DOI: 10.1371/journal.pone.0003383
Abstract Summary
Researchers found that blocking a specific step in plant metabolism causes toxic buildup rather than nutrient deficiency. When the GABA metabolic pathway is disrupted in Arabidopsis plants, accumulated intermediates SSA and GHB—not lack of energy molecules—trigger oxidative stress and stunted growth. This challenges assumptions about plant stress responses.
Why Brain? 🧠
Study reveals toxic metabolite buildup, not energy deficiency, causes severe oxidative stress in GABA pathway mutants, advancing understanding of plant stress responses and metabolic disease mechanisms.
The image is AI-generated for illustrative purposes only. Courtesy of Midjourney.
