Authors: Guillaume Paré, Daniel I. Chasman, Mark Kellogg, Robert Y. L. Zee, Nader Rifai, Sunita Badola, Joseph P. Miletich, Paul M. Ridker
DOI: 10.1371/journal.pgen.1000118
Abstract Summary
Genome-wide study of 6,578 women identifies genetic variants at ICAM1 and ABO loci strongly associated with circulating sICAM-1 levels, a biomarker linked to heart attack, stroke, and diabetes. Notably, the ABO blood group locus showed the strongest association, revealing a previously unknown role of blood type antigens in regulating inflammatory adhesion processes.
Why Brain? 🧠
Large genetic study of 6,578 women reveals ABO blood type affects levels of sICAM-1, an inflammatory marker linked to heart attack, stroke, and diabetes, suggesting blood type influences inflammation.
The image is AI-generated for illustrative purposes only. Courtesy of Midjourney.
