Monday, December 1, 2025

Lactobacillus casei Abundance Is Associated with Profound Shifts in the Infant Gut Microbiome

Authors: Michael J. Cox, Yvonne J. Huang, Kei E. Fujimura, Jane T. Liu, Michelle McKean, Homer A. Boushey, Mark R. Segal, Eoin L. Brodie, Michael D. Cabana, Susan V. Lynch

DOI: 10.1371/journal.pone.0008745

Abstract Summary

Probiotic supplementation with Lactobacillus rhamnosus (LGG) in 6-month-old infants promotes a more balanced and stable gut microbiome. High-density microarray analysis revealed that LGG encourages growth of beneficial bacterial species while creating a more evenly distributed microbial community—characteristics linked to better resistance against pathogens and disease. This stabilizing effect may explain how LGG protects against childhood allergies and asthma.

Why Brain? đź§ 

Probiotic supplementation with Lactobacillus casei in infants promotes a more stable, diverse gut microbiome that may protect against allergies and asthma by preventing harmful bacterial overgrowth.


The image is AI-generated for illustrative purposes only. Courtesy of Midjourney.

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