Erythropoietin Improves the Survival of Fat Tissue after Its Transplantation in Nude Mice

Authors: Saher Hamed, Dana Egozi, Danny Kruchevsky, Luc Teot, Amos Gilhar, Yehuda Ullmann

DOI: 10.1371/journal.pone.0013986

Abstract Summary

Erythropoietin (EPO) significantly improves fat graft survival in mice by boosting blood vessel formation and reducing cell death. EPO-treated grafts showed greater weight and volume retention after 15 weeks compared to controls, with effects comparable to VEGF treatment. This discovery could help solve the major challenge of fat resorption in reconstructive surgery.

Why Brain? 🧠

EPO treatment significantly improves fat graft survival in mice by boosting blood vessel formation and reducing cell death, offering a promising solution to the major clinical problem of fat resorption after transplantation.

The image is AI-generated for illustrative purposes only. Courtesy of Midjourney.