Authors: Mi Sung Park, Beom Kyung Kim, Jae Yoeun Cheong, Dong Joon Kim, Jun Yong Park, Do Young Kim, Sang Hoon Ahn, Kwang-Hyub Han, Chae Yoon Chon, Seung Up Kim
DOI: 10.1371/journal.pone.0055759
Abstract Summary
FibroTest, a non-invasive alternative to liver biopsy, accurately predicts liver fibrosis in hepatitis B patients. However, this study of 330 Asian patients found discordance in 9.1% of cases, primarily underestimating fibrosis severity. Advanced fibrosis (F3-4) was the only independent predictor of mismatch, with discordance rates five times higher in severe cases.
Why Brain? ðŸ§
FibroTest underestimates advanced liver fibrosis (F3-4) in 9% of Asian chronic hepatitis B patients compared to biopsy, potentially missing critical cases needing treatment.
The image is AI-generated for illustrative purposes only. Courtesy of Midjourney.
