Authors: Pierre Pouget, Nicolas Wattiez, Sophie Rivaud-Péchoux, Bertrand Gaymard
DOI: 10.1371/journal.pone.0005208
Abstract Summary
Researchers found that disrupting the balance of brain chemicals in monkeys’ prefrontal cortex dramatically increased performance inconsistency—a hallmark of ADHD. Blocking inhibitory signals caused erratic response times and movement accuracy, while enhancing them had minimal effect. This reveals how delicate brain chemistry affects attention and suggests new treatment approaches for ADHD.
Why Brain? 🧠
Disrupting GABA balance in monkey prefrontal cortex dramatically increases performance variability, mimicking ADHD symptoms and suggesting new therapeutic targets for attention disorders.
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