Authors: Yulei Wang, Catalin C. Barbacioru, Dov Shiffman, Sriram Balasubramanian, Olga Iakoubova, Maryann Tranquilli, Gonzalo Albornoz, Julie Blake, Necip N. Mehmet, Dewi Ngadimo, Karen Poulter, Frances Chan, Raymond R. Samaha, John A. Elefteriades
DOI: 10.1371/journal.pone.0001050
Abstract Summary
Researchers identified a 41-gene signature in peripheral blood that detects thoracic aortic aneurysm (TAA) with 78-80% accuracy. This blood-based test could enable early detection of TAA, a typically silent condition with high mortality. The gene expression patterns also distinguish TAA subtypes and offer insights into disease mechanisms, potentially revealing new therapeutic targets.
Why Brain? ðŸ§
Blood test using 41 genes detects deadly thoracic aortic aneurysms with 78-80% accuracy, offering potential for early screening of this usually silent condition before rupture occurs.
The image is AI-generated for illustrative purposes only. Courtesy of Midjourney.
