Sunday, October 19, 2025

Clinical Symptoms and Risk Factors in Cerebral Microangiopathy Patients

Authors: Sandra Okroglic, Catherine N. Widmann, Horst Urbach, Philip Scheltens, Michael T. Heneka

DOI: 10.1371/journal.pone.0053455

Abstract Summary

Cerebral microangiopathy shows distinct symptom patterns based on brain lesion location. Frontal lobe damage correlates with cognitive decline and gait problems, while other regions link to seizures and vertigo—symptoms previously overlooked. Key risk factors include aging, hypertension, and notably, obesity. With rising diagnoses, preventing vascular risk factors becomes crucial.

Why Brain? đź§ 

Study links brain small vessel disease location to specific symptoms like cognitive decline and gait problems. Identifies obesity as new risk factor alongside age and hypertension, emphasizing prevention.


The image is AI-generated for illustrative purposes only. Courtesy of Midjourney.

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