Authors: Basile Stamatopoulos, Nathalie Meuleman, Cécile De Bruyn, Karlien Pieters, Géraldine Anthoine, Philippe Mineur, Dominique Bron, Laurence Lagneaux
DOI: 10.1371/journal.pone.0012780
Abstract Summary
Researchers developed a powerful prognostic score for chronic lymphocytic leukemia using three RNA markers (ZAP70, LPL, and microRNA-29c). Testing 170 patients, the score stratified them into three risk groups with significantly different treatment-free and overall survival rates. This qPCR-based tool outperformed existing prognostic factors and may improve patient risk assessment at diagnosis.
Why Brain? 🧠
Novel qPCR score combining ZAP70, LPL, and microRNA-29c markers outperforms existing prognostic tools, stratifying CLL patients into three risk groups with significantly different survival outcomes at diagnosis.
The image is AI-generated for illustrative purposes only. Courtesy of Midjourney.
