Authors: Jean-Eric Blatteau, Alf O. Brubakk, Emmanuel Gempp, Olivier Castagna, Jean-Jacques Risso, Nicolas Vallée
DOI: 10.1371/journal.pone.0060639
Abstract Summary
Contrary to expectations, sildenafil (Viagra) worsened decompression sickness in rats. While nitric oxide-releasing agents show promise in preventing DCS, this study found sildenafil pre-treatment increased DCS symptoms from 6% to 34% and reduced platelet counts more than controls. These surprising results suggest divers using phosphodiesterase-5 inhibitors should consult physicians before diving.
Why Brain? 🧠
Study reveals sildenafil (Viagra) increases decompression sickness risk in divers by 5-fold, causing more severe neurological symptoms despite its blood vessel-dilating effects, urging caution for divers using this medication.
The image is AI-generated for illustrative purposes only. Courtesy of Midjourney.
