Authors: Nat F Brown, Bruce A Vallance, Brian K Coombes, Yanet Valdez, Bryan A Coburn, B. Brett Finlay
DOI: 10.1371/journal.ppat.0010032
Abstract Summary
New research reveals that Salmonella activates its key virulence system (SPI-2) much earlier than previously thought – while still in the intestinal lumen, before invading tissue. This early activation may help the pathogen prepare for survival within immune cells during systemic infection.
Why Brain? 🧠
New research reveals Salmonella activates its key virulence system SPI-2 before invading intestinal tissue, not after as previously thought. This early activation prepares the bacteria to survive inside immune cells, offering insights for developing better treatments against typhoid-like infections.
The image is AI-generated for illustrative purposes only. Courtesy of Midjourney.
