Lactobacillus Proteins Are Associated with the Bactericidal Activity against E. coli of Female Genital Tract Secretions

Authors: Sabah Kalyoussef, Edward Nieves, Ellen Dinerman, Colleen Carpenter, Viswanathan Shankar, Jamie Oh, Berta Burd, Ruth H. Angeletti, Karen W. Buckheit, David N. Fredricks, Rebecca P. Madan, Marla J. Keller, Betsy C. Herold

DOI: 10.1371/journal.pone.0049506

Abstract Summary

Female genital tract secretions show strong bactericidal activity against E. coli, with effectiveness varying widely between women. Research on 99 healthy women found that protective proteins from both host cells and beneficial Lactobacillus bacteria contribute to this natural defense mechanism.

Why Brain? 🧠

Study reveals Lactobacillus bacteria proteins in vaginal secretions kill harmful E. coli, explaining why some women have better natural protection against UTIs and infections.

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