Authors: Leonore Lovis, Tippi K. Mak, Khampheng Phongluxa, Phonepasong Ayé Soukhathammavong, Youthanavanh Vonghachack, Jennifer Keiser, Penelope Vounatsou, Marcel Tanner, Christoph Hatz, Jürg Utzinger, Peter Odermatt, Kongsap Akkhavong
DOI: 10.1371/journal.pntd.0001726
Abstract Summary
Higher-dose praziquantel (75 mg/kg) significantly outperformed standard dosing (40 mg/kg) against liver fluke infections in Laotian schoolchildren, achieving 96.6% vs 71.4% cure rates. Both doses showed similar effectiveness against schistosomiasis. The study highlights the importance of rigorous diagnostic testing for accurate treatment assessment.
Why Brain? 🧠
Study shows higher praziquantel dose (75mg/kg) significantly more effective than standard dose (40mg/kg) for treating liver fluke infections in Lao children, but rigorous testing needed to detect true cure rates.
The image is AI-generated for illustrative purposes only. Courtesy of Midjourney.
