Authors: Christel Steen, Nadine Wilczak, Johannes M. Hoogduin, Marcus Koch, Jacques De Keyser
DOI: 10.1371/journal.pone.0010811
Abstract Summary
New research reveals that multiple sclerosis patients show disrupted energy metabolism in brain tissue that appears normal on scans. Scientists found elevated phosphocreatine levels in progressive MS patients due to reduced creatine kinase B enzyme activity in astrocytes. This metabolic dysfunction may contribute to nerve damage in MS.
Why Brain? ðŸ§
Study reveals reduced creatine kinase B activity in MS brain tissue, suggesting impaired energy metabolism in astrocytes may contribute to nerve damage through glutamate toxicity.
The image is AI-generated for illustrative purposes only. Courtesy of Midjourney.
