Authors: Elizabeth J. Kelly, Elizabeth M. Hadac, Bryan R. Cullen, Stephen J. Russell
DOI: 10.1371/journal.ppat.1000820
Abstract Summary
Researchers engineered Coxsackievirus A21 with microRNA targets to study antiviral mechanisms. They discovered microRNAs block viruses at multiple stages: degrading viral RNA, suppressing translation, and preventing genome packaging. This work advances safer vaccine and cancer therapy development.
Why Brain? đź§
MicroRNAs can block virus replication at multiple stages – from genome destruction to protein translation to particle assembly – offering new strategies for safer vaccines and cancer therapies.
The image is AI-generated for illustrative purposes only. Courtesy of Midjourney.
