Authors: Sebastian Kummer, Stefanie Jeruschke, Lara Vanessa Wegerich, Andrea Peters, Petra Lehmann, Annette Seibt, Friederike Mueller, Nadezda Koleganova, Elisabeth Halbenz, Claus Peter Schmitt, Markus Bettendorf, Ertan Mayatepek, Marie-Luise Gross-Weissmann, Jun Oh
DOI: 10.1371/journal.pone.0027457
Abstract Summary
New research reveals why women have better outcomes in chronic kidney disease: estrogen directly protects key kidney cells called podocytes. Scientists found that estrogen receptors in podocytes prevent cell death and maintain kidney function through mitochondrial stabilization and cellular signaling pathways.
Why Brain? 🧠
Estrogen receptor alpha in kidney podocytes protects against cell death, explaining why women have better outcomes in chronic kidney disease than men.
The image is AI-generated for illustrative purposes only. Courtesy of Midjourney.
