Sunday, October 19, 2025

The Somatostatin Analogue Octreotide Inhibits Growth of Small Intestine Neuroendocrine Tumour Cells

Authors: Su-Chen Li, Cécile Martijn, Tao Cui, Ahmed Essaghir, Raúl M. Luque, Jean-Baptiste Demoulin, Justo P. Castaño, Kjell Öberg, Valeria Giandomenico

DOI: 10.1371/journal.pone.0048411

Abstract Summary

New research reveals octreotide, a key drug for neuroendocrine tumors, works through previously unknown pathways. Scientists discovered the drug activates six novel genes that control cell growth and differentiation, offering fresh insights into treatment mechanisms beyond traditional receptor targets.

Why Brain? 🧠

Octreotide, a cancer drug, works through novel genes beyond known receptors, potentially explaining why it helps patients with low receptor levels and offering new therapeutic targets.

The image is AI-generated for illustrative purposes only. Courtesy of Midjourney.

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