The Occurrence of Warfarin-Related Nephropathy and Effects on Renal and Patient Outcomes in Korean Patients

Authors: Jung Nam An, Shin Young Ahn, Chang-Hwan Yoon, Tae-Jin Youn, Moon-Ku Han, Sejoong Kim, Ho Jun Chin, Ki Young Na, Dong-Wan Chae

DOI: 10.1371/journal.pone.0057661

Abstract Summary

Warfarin-related nephropathy (WRN) affects 19.3% of patients with excessive blood thinning (INR >3.0), causing acute kidney injury. Korean study of 1,297 patients found low albumin, high liver enzymes, and heart failure increase WRN risk, while atrial fibrillation is protective. WRN leads to worse kidney function and higher mortality rates.

Why Brain? 🧠

Study of 1,297 Korean patients found warfarin-related nephropathy occurs in 19.3% with excessive anticoagulation, linked to worse kidney function and higher mortality, especially in those with heart failure.

The image is AI-generated for illustrative purposes only. Courtesy of Midjourney.